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Top 15 Hardest Science Courses In The World

Top 15 Hardest Science Courses In The World

Many students who enroll in a science course at university do not complete it.

Instead, because science courses are difficult, the majority of them drop out in their second year.

The courses’ difficulty stems from the abstract and dynamic nature of the concepts covered.

Furthermore, the Top 15 Hardest Science Courses have a lot of content and necessitate teacher-centered training as well as time commitment from the learner.

College graduates with a science degree typically have a plethora of job opportunities available to them, and once employed, benefit from high salaries and high levels of job security.

A science degree is not easy to obtain; the most successful science students have strong math skills, a natural curiosity, persistence, and the ability to work in a team.

Given that science is a broad field that includes majors ranging from biology to physics, some majors are more difficult than others.

The following is a list of the Top 15 Hardest Science Courses in science.

Top 15 Hardest Science Courses

1. Physics

Physics is the most difficult undergraduate degree to obtain at any university in the world.

One reason for this is that it places a high value on conceptual understanding of the subject matter.

Another factor that makes it difficult is that it is the foundation of many other sciences, including astronomy and chemistry.

Before enrolling in a physics program, a student must have a minimum GPA of 3.0 or an average grade of B (plain) or better in high school.

A student must also have at least a B (plain) in Physics and Mathematics. After graduation, a person can work as a physics teacher, astronomer, researcher, sound engineer, or nanotechnologist.

Physics is a difficult degree because there are no shortcuts to understanding it.

The truth about STEM subjects like Math and Science is that while there is a lot of information and formulas to memorize, simply knowing the correct answer isn’t enough.

You must comprehend why and how it is the correct answer. While rote learning equations and formulas may be acceptable in A-Level Physics, it will not be accepted at the degree level.

2. Chemistry

Chemistry is well-known for being one of the most difficult subjects ever, so it’s no surprise that a Chemistry degree is extremely difficult.

Organic chemistry, for example, is an extremely complex topic in Chemistry.

It encompasses more than 15 million compounds and an infinite number of organic chemical reactions to investigate, in addition to requiring massive amounts of memorization.

To put it another way, Chemistry combines biology and medicine, physics and mathematics, and environmental sciences.

Furthermore, the abstract nature of the chemical concepts involved complicates the situation.

As a result, the study necessitates time, dedication, subject knowledge, and a desire to learn.

Enrollment in A requires a GPA of at least 3.1 or a mean grade of B (plain). They must also pass Math, Chemistry, and either Physics or Biology.

After graduation, a person can work as a chemistry teacher, chemical engineer, toxicologist, water chemist, analytical chemist, or synthetic chemist.

3. Astronomy

An Astronomy degree requires you to study one of the most advanced branches of physics (Astrophysics), which gives you an idea of how difficult it is.

Astronomers, like any other hard science, must make falsifiable predictions about space and the universe, which they must test in a controlled environment.

As you continually experiment with hypotheses to try to reach a conclusion, sciences like astronomy inevitably involve a lot of failures.

It’s not the same as simply having an idea: if you can’t carry it out, it’s not worth much.

Astronomy also contains a significant amount of mathematics, which turns off many students.

You must be logical in order to perform basic special relativity calculations, as well as understand differential equations and linear algebra.

Astronomy, on the other hand, may be the subject for you if you enjoy exploring space, stars, and planets, as well as the very complex mathematics and physics behind them.

4. Computer Science

Computer Science is among the most difficult science degrees to obtain because it necessitates a thorough understanding of difficult topics such as computer software, technology, algorithms, statistics, and learning programming languages.

All of these subjects necessitate a significant amount of time and motivation from students in order for them to succeed.

If you have a GPA of 3.2 or a mean grade of B+ in high school, you can enroll in Computer Science. Some schools also require students to have a 70% average in four subjects, including math and physics.

After graduation, a student can work as a software engineer, data and application analyst, cyber security specialist, or game developer.

Computer scientists are in high demand, but you must be willing to commit to a rigorous major if you want to pursue one!

Rather than learning a specific set of curricula found in the hard sciences, computer science majors spend a lot of time troubleshooting and problem-solving.

Students majoring in computer science learn computational methods as well as computer theory and application, from informatics to systems.

5. Biomedical Science

Medicine is rightfully regarded as among the Top 15 hardest science courses, but did you know that Biomedical Science has a lot in common with Medicine?

In fact, Biomedical Science students must understand medicine in greater depth than most doctors!

To understand everything from human physiology, pathology, and microbiology, to hematology, cells, organs, and system function, you must work extremely hard in Biomedical Science.

Because of the breadth of knowledge, you may have to learn about things you’re not interested in (for example, learning all the names of pharmaceutical drugs!) in order to get a good grade.

As a Biomedical Science student, you must conduct extensive independent research in addition to learning and comprehending highly technical medical information.

However, if you are interested in science and medicine, Biomedical Science can be a very rewarding degree.

You’ll learn how Biomedical Science works from every angle, including research, policy, and industry, as well as diseases and conditions that have a significant impact on the human body.

6. Biology

Biology is a difficult science course to study because it is broad and focuses on life from various perspectives.

There are numerous branches and sub-disciplines that a student must learn and comprehend.

Furthermore, the program has some highly focused areas that necessitate a significant amount of time to study, research, and prepare for exams.

A minimum GPA of 3.0 or a mean grade of B is required for a student to pursue a degree in biology (plain).

Biology, English, and Mathematics, or Physics and Chemistry, are also required.

Following graduation, a person can work as a biology teacher, pharmacologist, research scientist, health educator, or genetic counsellor.

7. Neuroscience

Neuroscience is a fascinating degree, but it is extremely difficult.

As complex as the human brain is, it stands to reason that a subject devoted to it would be equally so.

Neuroscience is a multidisciplinary degree that includes many difficult subjects.

Organic chemistry, psychology, mathematics, physics, and cognitive science are among them.

One of these subjects sounds difficult enough on its own, but having to understand all of them in some capacity while studying neuroscience emphasizes how difficult this degree subject is.

Neuroscience is especially difficult to grasp because it combines the physical and the abstract.

There are so many mysteries about the human brain and consciousness that empirical science cannot fully explain, which is why Neuroscience includes philosophical aspects.

8. Nursing

Nursing is the most difficult science major to complete because students must study science topics such as chemistry, psychology, anatomy, and physiology.

Furthermore, the coursework is lengthy and complex due to the extensive lab work, hospital visits, and patient interaction.

A student can pursue a nursing degree if they have a GPA of at least 3.0 or a mean grade of B. (plain).

They must also have passed Biology, Chemistry, English, and Mathematics. A nursing degree allows you to work as a nurse, paramedic, midwife, or physician associate.

Nursing students work early morning and late-night shifts for their clinical, where they shadow real nurses and learn what it’s like to be a nurse. These encounters make for some intense hours.

If you want to sleep in while in college, a nursing degree will make that difficult!

Nursing students study anatomy, chemistry, biology, pharmacology, nutrition, and psychology in the classroom.

The standards are high: to remain in many programs, you must maintain a minimum 3.0 GPA.

9. Molecular Cell Biology

Molecular Cell Biology is one of the most difficult Biology degrees to obtain, and Biology is a difficult discipline in and of itself.

Learning Molecular Cell Biology is similar to learning a new language because the vocabulary used to describe the structure and function of life at the molecular level is extremely complex.

Prepare to memorize a lot of names!

You must also have a deep understanding of extremely technical processes, such as the relationship between proteins and nucleic acids, as well as the molecular mechanisms of immunology, genetic engineering, and cancer.

To do well in this degree, you’ll need to understand very complex areas of biomedicine and biotechnology.

Biology subjects are frequently misunderstood as not requiring a lot of math, but anyone who believes this is gravely mistaken.

When you start your first year of a Molecular Cell Biology degree, you’re likely to be studying genetics, as well as microbiology and animal and plant biology.

Genetics is a math-intensive field because geneticists use very complex equations.

10. Astrophysics

Astrophysics is a discipline of physics. But what makes the course more difficult is that it includes a lot of advanced mathematics and physics.

Furthermore, the subject necessitates a great deal of memorization, calculations, and late-night studying.

A student who wishes to pursue Astrophysics at the university level must have a strong background in mathematics and physics.

In other words, they must have received at least an 80 percent on the two subjects.

However, after graduation, they will be able to work as an astrophysicist, physics teacher, astronomer, astronaut, or aerospace research specialist.

11. Mathematics

Most of us developed a personal aversion to mathematics in school. As a result, it’s no surprise that it’s on this list of the most difficult college majors.

Any level of mathematics degree involves a significant amount of reasoning, critical thinking, formulas, and other technicalities.

A mathematics major’s courses cover either general, pure, or applied mathematics.

Algebra, differential calculus, geometry, statistics, and probability are some of the fundamental subjects covered in all courses.

Topology and foundations, analysis and functional analysis, algebra and number theory, geometric analysis, and applied mathematics are some of the specializations available in this major.

If you have a GPA of at least 3.0, you can major in Mathematics. To enroll in the program, you must also have a passing grade in Mathematics of at least 75%.

After graduation, you will be able to work as a mathematics teacher, accountant, statistician, economist, or market researcher.

12. Biomedical Engineering

Because it combines biology and engineering, Biomedical Engineering appears to be the most difficult science.

It teaches students how to design medical devices and therapies, plan experiments, analyze and interpret data, and develop solutions using engineering principles.

As a result, a student’s motivation, concentration, and time commitment are all required for success.

To study Biomedical Engineering, you must have a GPA of at least 3.2 or a mean grade of B+ with a higher score in Mathematics, Biology, English, or Physics and Chemistry.

After graduation, you could work as a biomaterials engineer, biomedical researcher, or medical imaging consultant.

13. Statistics

Statistics is a more difficult course than most people believe. This is correct; the level of difficulty of this course can only be understood if you enroll in it and begin learning it.

The collection of a large amount of data in tables is inherently complex. This is correct; have you attempted to comprehend the course? It is extremely difficult.

The course necessitates a high level of memory as well as a large number of formulas, theories, and tests. Statistics is a difficult course because of all of these factors.

Even though an objective view exists, the debate over which college major is the most difficult and which is the easiest to complete is highly subjective.

When choosing a major, you should consider other factors such as passion for a field and employment prospects rather than difficulty level.

This is due to the fact that, contrary to popular belief, the easier a major does not necessarily imply that you will not study hard to pass it.

14. Molecular Engineering

Molecular Engineering 9 Because it is a new field of study, Molecular Engineering is a difficult course to take.

Furthermore, because it combines many aspects of chemical, electrical, and mechanical engineering as well as physics, chemistry, mathematics, materials science, and bioengineering, the degree is highly interdisciplinary.

As a result, a student must study all of these subjects, which can be difficult. Because Molecular Engineering is an engineering course, a student must have a GPA of at least 3.0.

They must also have higher grades in all required subjects, which include Mathematics, Chemistry, Biology, and Physics.

After graduation, a person can work as a mechanical engineer, nanotechnologist, researcher, or robotics specialist.

15. Biochemistry


According to data from the National Survey of Student Engagement (NSSE), is among the Top 15 Hardest Science Courses especially in terms of average hours spent in class.

It is unsurprising that it is regarded as one of the world’s most difficult courses. Biochemistry is the study of the chemical processes and substances found in living organisms, as well as the application of fundamental physics principles to the study of organisms and biological phenomena.


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It requires the retention of a large number of facts as well as the understanding of abstract concepts.

Genetics, cell biology, neurobiology, evolutionary biology, and computing are among the topics covered in specialized classes, so biology, chemistry, physics, and math are required.

Top 15 Hardest Science Courses In The World

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